Medical Marijuana for Chronic pain

IMPORTANCE:
As of March 2015, 23 states and the District of Columbia had medical marijuana laws in
place. Physicians should know both the scientific rationale and the practical implications for
medical marijuana laws.
OBJECTIVE:
To review the pharmacology, indications, and laws related to medical marijuana use.
EVIDENCE REVIEW:
The medical literature on medical marijuana was reviewed from 1948 to March 2015 via
MEDLINE with an emphasis on 28 randomized clinical trials of cannabinoids as
pharmacotherapy for indications other than those for which there are 2 US Food and Drug
Administration-approved cannabinoids (dronabinol and nabilone), which include nausea and
vomiting associated with chemotherapy and appetite stimulation in wasting illnesses.
FINDINGS:
Use of marijuana for chronic pain, neuropathic pain, and spasticity due to multiple sclerosis is
supported by high-quality evidence. Six trials that included 325 patients examined chronic
pain, 6 trials that included 396 patients investigated neuropathic pain, and 12 trials that
included 1600 patients focused on multiple sclerosis. Several of these trials had positive
results, suggesting that marijuana or cannabinoids may be efficacious for these indications.
CONCLUSIONS AND RELEVANCE:
Medical marijuana is used to treat a host of indications, a few of which have evidence to
support treatment with marijuana and many that do not. Physicians should educate patients
about medical marijuana to ensure that it is used appropriately and that patients will benefit
from its use

At Omega Health & Wellness here in Jacksonville,  FL our physicians stay current on information that is important to the care our patients receive.


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