hCG for Testicular function
In men, LH stimulates testosterone production from the interstitial cells of the testes (Leydig cells). Leydig cells are only found in the testes and are the only cells of significance in the body to produce testosterone. FSH stimulates testicular growth and enhances the production of an androgen-binding protein by the Sertoli cells. With prolonged usage of testosterone therapy men will often have a decrease in their testicular functions resulting in a lowering of the LH and FSH.
Human Chorionic Gonadotropin (hCG) chemically is a double polypeptide -glycoprotein hormone, which acts like the anterior pituitary hormone called luteinizing hormone (LH). Luteinizing hormone is the normal primary activator for testosterone synthesis by the Leydig by acting on cell receptors. hCG is an analog to LH (acts like LH and fits into Leydig cell receptors) and activates Leydig cells to make testosterone. If the Leydig cells are sufficient in number and are functional you should see an increase in serum testosterone.
This is part of our hormone replacement therapy.